Definition/General
Clinical Features
Master Paget Disease Pathology with RxDx
Access 100+ pathology videos and expert guidance with the RxDx app
Gross Description
Microscopic Description
Immunohistochemistry
Molecular/Genetic
Differential Diagnosis
Sample Pathology Report
Template Format
Sample Pathology Report
Complete Report: This is an example of how the final pathology report should be structured for this condition.
Specimen Information
Vulvar excision, [site], measuring [size] cm in greatest dimension
Diagnosis
Vulvar Paget disease, [primary/secondary if known]
Classification
Classification: [Intraepithelial/Invasive], extent: [superficial/full-thickness]
Histological Features
Shows [Paget cell distribution] with [cellular morphology] and [epidermal changes]
Invasion Status
Invasive component: [present/absent], depth: [X mm if present]
Margins
Margins are [clear/involved] with Paget cells [X] mm from closest margin
Lymphovascular Invasion
Lymphovascular invasion: [present/absent]
Extent of Involvement
Paget cells involve [epidermal layers] and [adnexal structures]
Special Studies
IHC: CK7: [positive/negative], CEA: [result], CDX2: [result]
Molecular: [test performed]: [result]
[other study]: [result]
Prognostic Factors
Prognostic factors: invasive component, margins, multifocal disease
Final Diagnosis
Vulvar Paget disease, [intraepithelial/invasive], margins [status]