Definition/General
Clinical Features
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Gross Description
Microscopic Description
Immunohistochemistry
Molecular/Genetic
Differential Diagnosis
Sample Pathology Report
Template Format
Sample Pathology Report
Complete Report: This is an example of how the final pathology report should be structured for this condition.
Specimen Information
[specimen type], measuring [size] cm in greatest dimension
Diagnosis
Vulvar Minimal Deviation Adenocarcinoma
Classification
Classification: Adenocarcinoma, minimal deviation type (adenoma malignum)
Histological Features
Shows well-formed glands with [minimal atypia] and [infiltrative pattern]
Size and Extent
Size: [X] cm, extent: [deep infiltration present]
Margins
Margins are [involved/uninvolved] with closest margin [X] mm
Infiltration Pattern
Shows [haphazard glandular arrangement] with [deep stromal infiltration]
Immunohistochemistry
CEA: [positive/negative], MUC6: [positive/negative]
p63: [negative], p16: [negative]
HIK1083: [positive/negative]
Genetic Correlation
Consider [Peutz-Jeghers syndrome] evaluation and [genetic counseling]
Prognostic Factors
Tumor size, infiltration depth, margin status, genetic syndrome association
Final Diagnosis
Vulvar Minimal Deviation Adenocarcinoma (Adenoma malignum)