Definition/General
Clinical Features
Master Apocrine Carcinoma Pathology with RxDx
Access 100+ pathology videos and expert guidance with the RxDx app
Gross Description
Microscopic Description
Immunohistochemistry
Molecular/Genetic
Differential Diagnosis
Sample Pathology Report
Template Format
Sample Pathology Report
Complete Report: This is an example of how the final pathology report should be structured for this condition.
Specimen Information
[specimen type], measuring [size] cm in greatest dimension
Diagnosis
Vulvar Apocrine Carcinoma
Classification
Classification: Adenocarcinoma with apocrine differentiation, Grade [I/II/III]
Histological Features
Shows apocrine differentiation with [large eosinophilic cells] and [apical snouts]
Size and Extent
Size: [X] cm, extent: [local invasion present/absent]
Grade Assessment
Grade [I/II/III] based on [nuclear atypia], [architecture], and [mitotic activity]
Margins
Margins are [involved/uninvolved] with closest margin [X] mm
Apocrine Differentiation
Apocrine features: [decapitation secretion], [eosinophilic cytoplasm], [apical snouts]
Immunohistochemistry
GCDFP-15: [positive/negative], AR: [positive/negative]
CK7: [positive], EMA: [positive]
ER: [negative], PR: [negative], p63: [negative]
Prognostic Factors
Tumor grade, size, AR status, margin status
Final Diagnosis
Vulvar Apocrine Carcinoma (Adenocarcinoma with apocrine differentiation, Grade [I/II/III])