Definition/General
Clinical Features
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Gross Description
Microscopic Description
Immunohistochemistry
Molecular/Genetic
Differential Diagnosis
Sample Pathology Report
Template Format
Sample Pathology Report
Complete Report: This is an example of how the final pathology report should be structured for this condition.
Specimen Information
Vaginal biopsy/excision from [location] measuring [size] cm
Diagnosis
Adenocarcinoma of vagina, [subtype]
Classification and Grade
[Endometrioid/Clear cell/Mucinous/Serous] adenocarcinoma, Grade [1/2/3]
Histological Features
Shows [architectural pattern] with [cellular characteristics] and [degree] nuclear atypia
Invasion and Extent
Depth of invasion: [X] mm, extent: [superficial/deep stromal/paravaginal]
Margins
Margins are [involved/uninvolved], closest margin [X] mm from tumor
Lymphovascular Invasion
Lymphovascular invasion: [present/absent]
Special Studies
CK7: [positive/negative], PAX8: [positive/negative], ER: [positive/negative], PR: [positive/negative]
[Subtype-specific markers]: [results]
Ki-67 index: [percentage]%
FIGO Staging
FIGO Stage: [I/II/III/IV] - [staging description]
Prognostic Factors
Subtype: [type], Grade: [1/2/3], Stage: [I/II/III/IV], LVI: [present/absent]
Final Diagnosis
Primary vaginal [subtype] adenocarcinoma, Grade [1/2/3], FIGO Stage [I/II/III/IV]