Definition/General
Clinical Features
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Gross Description
Microscopic Description
Immunohistochemistry
Molecular/Genetic
Differential Diagnosis
Sample Pathology Report
Template Format
Sample Pathology Report
Complete Report: This is an example of how the final pathology report should be structured for this condition.
Specimen Information
Ovarian mass, [side], measuring [X x Y x Z] cm, weighing [X] grams
Diagnosis
Granulosa Cell Tumor, [Adult/Juvenile] Type
Classification
WHO Classification: Sex Cord-Stromal Tumor, Granulosa Cell Tumor
Histological Features
Shows [growth pattern] with characteristic coffee-bean nuclei and [presence/absence] of Call-Exner bodies
Size and Extent
Tumor size: [X] cm, [unilateral/bilateral], capsule [intact/breached]
Hormonal Effects
Associated with [estrogenic/androgenic/no] hormonal effects
Special Studies
IHC: Inhibin-alpha [positive/negative], Calretinin [positive/negative], FOXL2 [positive/negative]
Molecular: FOXL2 C134W mutation [detected/not detected]
Hormone levels: [specify results]
Prognostic Factors
Stage: [I/II/III/IV], Size: [>10 cm], Type: [Adult/Juvenile], Capsular involvement: [yes/no]
Final Diagnosis
Ovarian Granulosa Cell Tumor, [Adult/Juvenile] Type, [Stage], [Side]