Definition/General
Clinical Features
Master Undifferentiated Carcinoma Pathology with RxDx
Access 100+ pathology videos and expert guidance with the RxDx app
Gross Description
Microscopic Description
Immunohistochemistry
Molecular/Genetic
Differential Diagnosis
Sample Pathology Report
Template Format
Sample Pathology Report
Complete Report: This is an example of how the final pathology report should be structured for this condition.
Specimen Information
Hysterectomy specimen measuring [X x Y x Z] cm, weighing [X] grams
Diagnosis
Endometrial undifferentiated carcinoma
Classification
WHO Classification: Undifferentiated carcinoma, FIGO Grade: High-grade
Histological Features
Sheets of undifferentiated cells lacking glandular or specific differentiation
Associated Differentiated Component
[Present/Absent]: [type if present] ([percentage]%)
Size and Extent
Tumor size: [X] cm, myometrial invasion: [depth/total thickness], [percent]%
Margins
Margins: [involved/uninvolved], closest margin: [X] mm
Lymphovascular Invasion
Lymphovascular invasion: [present/absent]
Cervical Involvement
Cervical involvement: [present/absent]
Special Studies
IHC: Cytokeratins: [result], PAX8: [result], p53: [pattern]
Mismatch repair proteins: MLH1: [result], MSH2: [result], MSH6: [result], PMS2: [result]
Molecular studies: [if performed]
Microsatellite Instability
MSI status: [MSI-high/MSS/not tested]
FIGO Staging
FIGO Stage: [stage] ([staging criteria])
Prognostic Factors
High-grade tumor, Stage: [X], MSI status: [status]
Final Diagnosis
Endometrial undifferentiated carcinoma, FIGO Stage [X]