Definition/General
Clinical Features
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Gross Description
Microscopic Description
Immunohistochemistry
Molecular/Genetic
Differential Diagnosis
Sample Pathology Report
Template Format
Sample Pathology Report
Complete Report: This is an example of how the final pathology report should be structured for this condition.
Specimen Information
[specimen type], measuring [size] cm in greatest dimension
Diagnosis
Endometrial adenocarcinoma, signet ring cell variant
WHO Classification
Endometrial adenocarcinoma, special variant (signet ring cell type)
Histological Features
Signet ring cells with intracytoplasmic mucin, [percentage]% of tumor
Grade
FIGO Grade: 3 (high-grade by definition)
Myometrial Invasion
Myometrial invasion: [depth] mm, [percentage]% of wall thickness
Lymphovascular Invasion
Lymphovascular invasion: [present/absent]
Special Stains and Immunohistochemistry
Mucin stains: Mucicarmine [+/-], PAS [+/-]
Epithelial markers: CK7 [+/-], EMA [+/-]
p53: [overexpressed/wild-type/null], ER: [+/-]
Final Diagnosis
Endometrial adenocarcinoma, signet ring cell variant, FIGO Grade 3