Overview

Definition: Thyroid surgery nerve monitoring refers to the intraoperative use of electrophysiological techniques to identify and preserve critical nerves, primarily the recurrent laryngeal nerve (RLN) and external branch of the superior laryngeal nerve (EBSLN), during thyroidectomy to minimize the risk of vocal cord paralysis.
Epidemiology:
-While transient vocal cord paresis occurs in 5-10% of thyroidectomies, permanent paralysis rates are significantly lower, around 1-2%
-Neuromonitoring is increasingly adopted to further reduce these risks, particularly in complex cases or high-volume centers.
Clinical Significance:
-Preservation of vocal cord function is paramount for voice quality, airway patency, and aspiration prevention
-Nerve monitoring is crucial for surgeons to confidently identify nerve integrity, leading to improved patient outcomes and reduced postoperative morbidity, making it a vital skill for DNB and NEET SS preparation.

Indications For Monitoring

Standard Indications:
-Bilateral thyroid surgery
-Reoperative thyroid surgery
-Large goiters compressing the trachea or esophagus
-Thyroid malignancy with suspected or confirmed nerve involvement
-History of previous neck surgery or radiation.
Controversial Indications:
-Previous ipsilateral vocal cord dysfunction
-High-risk patients with comorbidities
-Certain surgeon preferences or institutional protocols
-Minimally invasive thyroidectomy techniques.
Contraindications:
-Generally no absolute contraindications, but patient factors affecting electrode placement or signal acquisition may be considered
-Extreme urgency of surgery might preclude detailed setup.

Nerve Monitoring Setup

Equipment:
-Electromyography (EMG) monitoring system with appropriate software
-Stimulator probe (monopolar or bipolar)
-Recording electrodes (needle or surface)
-Ground electrodes
-Return electrodes
-Integrated anesthesia and OR systems.
Electrode Placement:
-Recording electrodes placed in the cricothyroid muscle (for EBSLN) and/or thyroarytenoid muscle (for RLN) via endotracheal tube ports
-Ground electrodes on the patient (e.g., sternum or clavicle)
-Stimulator probe placed on the vagus nerve (often identified behind the carotid artery) or directly on the thyroid lobe near the nerve.
System Calibration:
-Preoperative baseline EMG recording
-System check for signal integrity
-Impedance checks for all electrodes
-Verification of stimulus threshold and waveform
-Adjusting gain and filtering settings for optimal signal-to-noise ratio.
Anesthesia Considerations:
-Use of non-depolarizing muscle relaxants is generally avoided or used with caution as they can inhibit nerve signal transmission
-TIVA (Total Intravenous Anesthesia) is preferred
-Adequate depth of anesthesia to prevent patient movement but not so deep as to abolish neural signals.

Intraoperative Nerve Identification And Monitoring

Vagus Nerve Identification:
-Locate the vagus nerve in the tracheoesophageal groove, typically posterior to the carotid artery and lateral to the trachea
-Careful dissection is required to expose it without injury.
Stimulator Probe Use:
-Gentle stimulation of the vagus nerve at a suprathreshold level to elicit a consistent EMG response
-Stimulation of the nerve directly on the thyroid lobe after its identification is also common practice.
Electromyography Response:
-Monitoring for a characteristic EMG waveform (e.g., triphasic) in the laryngeal muscles following vagal stimulation
-The amplitude and latency of the evoked response are key parameters.
Interpreting Emg Signals:
-A clear, reproducible twitch of the vocal cord and corresponding EMG signal indicate nerve integrity
-Transient signal loss or significant amplitude reduction requires immediate cessation of dissection and reassessment
-Complete signal loss is a red flag for potential permanent injury.

Types Of Nerve Monitoring

Intermittent Stimulation:
-Stimulating the vagus nerve or its branches at intervals during the procedure
-Historically common but less informative than continuous monitoring.
Continuous Nerve Monitoring:
-Continuous EMG monitoring of the laryngeal muscles, allowing for real-time detection of nerve irritation or injury
-This is the current gold standard and preferred method in most DNB and NEET SS curricula.
Specific Nerve Monitoring:
-Focus on specific nerves: RLN monitoring (standard)
-EBSLN monitoring (particularly important for certain thyroid procedures or when RLN is compromised)
-Trigeminal nerve monitoring (rarely used in thyroid surgery, more relevant in other head and neck procedures).

Complications And Management Of Nerve Injury

Prevention Strategies:
-Meticulous surgical technique
-Anatomical identification of nerves
-Avoidance of electrocautery near nerves
-Gentle retraction
-Appropriate use of nerve monitoring
-Understanding the branching patterns of the RLN and EBSLN.
Recognizing Intraoperative Injury:
-Sudden loss or significant reduction in EMG amplitude
-Absence of vocal cord movement on laryngoscopy
-Changes in intraoperative evoked potentials
-Palpable or visible injury to the nerve.
Management Of Intraoperative Injury:
-Immediate cessation of dissection in the area
-Re-identification and assessment of the nerve
-If nerve is transected, attempt immediate microsurgical repair
-If injury is suspected but not confirmed, close monitoring and potential vocal cord medialization post-operatively
-Documentation of the event and findings.

Key Points

Exam Focus:
-Understand the indications for nerve monitoring
-Know the equipment and setup
-Be able to interpret EMG waveforms and interpret signal loss
-Recognize strategies for preventing and managing nerve injury during thyroidectomy.
Clinical Pearls:
-Always confirm the baseline EMG response before significant dissection
-The presence of a clear EMG signal does not guarantee a good voice post-op, but its absence is a strong predictor of dysfunction
-Document all nerve monitoring findings rigorously.
Common Mistakes:
-Using muscle relaxants that inhibit EMG signals
-Inadequate stimulation intensity
-Misinterpreting artifacts as neural signals
-Over-reliance on visual identification alone without electrophysiological confirmation
-Failure to document critical monitoring events.