Overview

Definition:
-Thoracic empyema decortication is a surgical procedure involving the removal of a thickened, inelastic peel (necrotic tissue, fibrin, and fibrous membrane) from the visceral and parietal pleura
-This peel encases the lung, restricting its expansion, and is typically a consequence of chronic or inadequately treated pleural infection (empyema)
-Open decortication usually refers to a thoracotomy approach, providing direct access to the pleural space.
Epidemiology:
-Empyema incidence varies globally, often linked to pneumonia, thoracic surgery, trauma, and aspiration
-Community-acquired empyema is more common than hospital-acquired
-Risk factors include advanced age, immunosuppression, diabetes, and alcoholism
-The incidence of chronic, fibrotic empyema requiring decortication is lower but significant.
Clinical Significance:
-Untreated or chronic empyema can lead to significant morbidity and mortality due to persistent infection, lung parenchymal destruction, and respiratory compromise
-Decortication is crucial for lung re-expansion, resolution of infection, pain relief, and restoration of pulmonary function
-It is a vital procedure for surgical residents to understand for managing complex pleural diseases.

Indications

Indications For Decortication:
-Failure of initial drainage (tube thoracostomy) to resolve empyema
-Formation of a thick, inelastic peel encasing the lung, visualized on imaging (CT scan)
-Persistent fever and sepsis despite antibiotic therapy and drainage
-Loculated effusions that cannot be adequately drained by closed methods
-Trapped lung syndrome secondary to chronic empyema.
Timing Of Surgery:
-Ideal timing is usually after the acute inflammatory phase has subsided but before extensive fibrosis makes the peel intractable
-Typically, this is between 1 to 4 weeks after the onset of empyema, but may be delayed in chronic cases
-Early decortication can be performed in select cases if initial drainage fails.
Contraindications:
-Absolute contraindications are rare but include severe comorbid conditions precluding major surgery or anesthesia
-Relative contraindications include unreconstructable lung parenchymal disease, uncontrolled sepsis, or severe coagulopathy
-Patient optimization is key.

Diagnostic Approach

History And Physical Exam:
-Key history points include onset and duration of symptoms, preceding pneumonia or surgery, sputum production, pleuritic chest pain, and fever
-Physical examination may reveal tachypnea, decreased breath sounds, dullness to percussion, and egophony over the affected area.
Imaging Modalities:
-Chest X-ray (initial diagnosis of pleural effusion)
-Ultrasound (assessing for complexity and guiding aspiration/drainage)
-CT scan of the thorax (essential for delineating the empyema, assessing peel thickness, loculations, and lung involvement, guiding surgical approach)
-MRI may be useful for soft tissue evaluation.
Laboratory Investigations:
-Complete Blood Count (leukocytosis, anemia of chronic disease)
-Inflammatory markers (CRP, ESR)
-Sputum microscopy, culture, and sensitivity (identifying organism)
-Pleural fluid analysis (pH, glucose, protein, LDH, cell count, Gram stain, culture, cytology)
-Blood cultures if sepsis is suspected.
Differential Diagnosis:
-Complicated parapneumonic effusion
-Malignant pleural effusion
-Hemothorax
-Chylothorax
-Benign pleural tumors
-Organization of pulmonary infarct.

Surgical Procedure

Preoperative Preparation:
-Optimization of nutritional status, correction of anemia, control of comorbidities (diabetes, cardiac issues), adequate antibiotic coverage, and ensuring adequate pulmonary function
-Bronchodilators and respiratory physiotherapy may be initiated
-Preoperative bronchoscopy can be considered if suspicion of endobronchial obstruction.
Anesthesia And Positioning:
-General anesthesia with double-lumen endotracheal tube for single-lung ventilation is typically used
-The patient is positioned in a lateral decubitus position on the contralateral side, allowing optimal access to the hemithorax.
Thoracotomy Approach:
-A posterolateral thoracotomy incision is most common, providing excellent exposure of the entire hemithorax
-Rib-spreading retractors are used to open the intercostal space
-The parietal pleura is carefully dissected to expose the pleural cavity.
Decortication Technique:
-The peel is meticulously dissected from the visceral and parietal pleura, often starting from the hilum and working peripherally
-Careful attention is paid to avoid injury to the lung parenchyma and major vessels
-Hemostasis is paramount
-Once the peel is removed, the lung should expand spontaneously or with positive pressure ventilation
-Chest tubes are inserted for drainage and re-expansion.

Postoperative Care

Pain Management:
-Aggressive pain control is crucial for early mobilization and pulmonary physiotherapy
-Epidural analgesia, patient-controlled analgesia (PCA) with opioids, and non-opioid analgesics are utilized
-Intercostal nerve blocks may also be considered.
Chest Tube Management:
-Chest tubes are typically connected to an underwater seal drainage system, with or without suction
-Monitoring of drainage volume, character, and air leaks is essential
-Chest tubes are usually removed when drainage is minimal and lung expansion is satisfactory, as confirmed by imaging.
Respiratory Physiotherapy:
-Early ambulation, deep breathing exercises, incentive spirometry, and chest physiotherapy are vital to prevent atelectasis, pneumonia, and promote full lung expansion
-Mobilization of the patient should commence as soon as pain is controlled.
Monitoring:
-Close monitoring of vital signs, respiratory status, fluid balance, and signs of infection
-Serial chest X-rays to assess lung re-expansion and pleural space
-Monitoring for complications such as bronchopleural fistula, recurrent empyema, or bleeding.

Complications

Early Complications:
-Hemorrhage (from pleural adhesions or lung parenchyma injury)
-Persistent air leak
-Bronchopleural fistula (BPF)
-Recurrent empyema
-Pneumonia
-Atelectasis
-Injury to surrounding structures (phrenic nerve, intercostal vessels)
-Hemodynamic instability.
Late Complications:
-Chronic pain syndrome
-Restrictive lung disease
-Situs inversus or abnormal lung anatomy due to scarring
-Re-accumulation of pleural fluid
-Persistent cough
-Empyema necessitatis.
Prevention And Management:
-Meticulous surgical technique to minimize bleeding and air leaks
-Adequate chest tube drainage
-Prompt recognition and management of BPF (e.g., bronchoscopy with plugging, re-exploration)
-Aggressive physiotherapy to prevent atelectasis and pneumonia
-Early antibiotic therapy for suspected recurrent infection.

Prognosis

Factors Influencing Outcome:
-The extent of lung parenchymal damage, patient's overall health status, adequacy of surgical resection, and promptness of treatment initiation significantly impact prognosis
-Early and complete decortication generally leads to better outcomes.
Expected Outcomes:
-Successful decortication usually results in complete resolution of infection, lung re-expansion, relief of symptoms, and improvement in pulmonary function
-Most patients experience a significant return to normal activity levels over several months.
Follow Up:
-Regular clinical follow-up is recommended, typically including chest X-rays, to monitor for recurrence of effusion, lung expansion, and overall recovery
-Pulmonary function tests may be performed to assess functional improvement
-Long-term follow-up may be required for patients with significant lung damage or chronic sequelae.

Key Points

Exam Focus:
-Understand the stages of empyema (acute, organizing, chronic/fibrotic)
-Recognize imaging findings suggestive of peel formation
-Know the indications for decortication versus less invasive procedures
-Master the surgical steps and potential complications of open decortication.
Clinical Pearls:
-The "gold standard" for diagnosis of a peel dictating need for decortication is CT scan
-Distinguish between simple pleural effusions and empyema requiring drainage
-Meticulous dissection is key to avoiding pleural injury and parenchyma damage during decortication
-Lung entrappment is the primary indication for this procedure.
Common Mistakes:
-Inadequate drainage of empyema, leading to chronicity
-Delaying surgical intervention until extensive fibrosis makes decortication difficult or impossible
-Incomplete peel removal
-Aggressive dissection leading to lung parenchymal injury or air leaks
-Insufficient postoperative pain management or physiotherapy.