Overview

Definition:
-Seton placement is a surgical technique used in the management of complex anal fistulas, particularly those involving a significant portion of the external anal sphincter
-A seton is a drain or suture that is passed through the internal opening of the fistula, tract, and external opening, and then secured externally
-Its primary role is to provide gradual drainage, allow healing of the fistula tract, and prevent the formation of abscesses while preserving sphincter function.
Epidemiology:
-Anal fistulas affect approximately 1-3% of the general population, with a higher incidence in males
-Complex fistulas, those requiring seton placement, account for a significant proportion and are often associated with Crohn's disease, prior perianal sepsis, or high trans-sphincteric/suprasphincteric tracts
-The incidence of complex fistulas necessitates understanding of seton techniques for successful management.
Clinical Significance:
-Complex anal fistulas can lead to significant morbidity, including pain, recurrent abscesses, sepsis, and fecal incontinence if managed improperly
-Seton placement is crucial for preventing incontinence by allowing slow healing and sphincter preservation, making it a vital skill for surgeons preparing for DNB and NEET SS examinations who will encounter such cases in their practice
-Effective management improves patient quality of life and reduces re-operation rates.

Indications

Indications For Seton Placement:
-Primary indication is for complex anal fistulas
-This includes high trans-sphincteric fistulas (where more than 30% of the sphincter is involved) and suprasphincteric fistulas
-Other indications include recurrent anal abscesses, fistulas in patients with inflammatory bowel disease (e.g., Crohn's disease), actively draining fistulas that are not amenable to immediate fistulotomy, and as a preparatory step for staged procedures to avoid incontinence
-In some cases, it may be used for fistula tract maturation prior to definitive surgery.
Contraindications:
-Absolute contraindications are rare but include uncontrolled sepsis or abscess that requires immediate drainage, and a patient's inability to tolerate a prolonged treatment course
-Relative contraindications include very low-risk fistulas where simpler methods might suffice, and significant comorbidities that could compromise healing
-Poor patient compliance is also a significant concern.
Goals Of Seton Therapy:
-The main goals are to promote gradual healing of the fistula tract, allow for complete drainage, prevent recurrent abscess formation, and preserve anal sphincter function
-Setons act as a foreign body to encourage fibrosis and tract closure or as a drain to keep the tract open and draining pus
-The choice of seton and technique depends on the fistula anatomy and the surgeon's preference.

Types Of Setons

Draining Setons:
-These setons are typically made of latex rubber tubing or silicone bands
-They are passed through the fistula tract and secured externally, usually by tying the ends together
-The purpose is to maintain drainage of pus and exudate, thereby preventing abscess formation and encouraging granulation and healing of the tract from the inside out
-These are often used for longer-term management.
Cutting Setons:
-These are usually made of strong silk or braided polyester suture material
-They are gradually tightened over time, typically by a few millimeters every few days or weeks
-The gradual tightening cuts through the surrounding tissue, including the sphincter muscle, leading to a slow division of the fistula tract and sphincter
-This method aims for eventual healing with minimal loss of sphincter function.
Loose Setons:
-These setons are left loosely in the fistula tract and are not tightened
-They are primarily used to keep the tract patent for drainage and to prevent closure of the internal opening before the external opening has healed, thus avoiding abscesses
-They are often used in the initial management of complex fistulas or in patients with IBD.

Surgical Technique

Preoperative Assessment:
-A thorough history and physical examination are essential
-Imaging modalities like MRI fistula protocol or endoanal ultrasound are crucial for defining the fistula tract anatomy, including its relation to the sphincters and identifying any associated abscesses
-Preoperative antibiotics may be administered
-Bowel preparation might be considered for some procedures.
Seton Insertion Procedure:
-The procedure is typically performed under anesthesia
-After identifying the internal and external openings, a probe or guidewire is passed through the fistula tract
-The chosen seton material is then threaded through the tract
-For draining setons, the ends are tied loosely
-For cutting setons, the suture is tied snugly, and gradual tightening is planned
-For loose setons, the material is placed and secured without tension.
Postoperative Care Initial:
-Pain management is paramount, typically with analgesics
-Patients are usually advised to keep the perineal area clean and dry
-Warm sitz baths may be recommended starting 24-48 hours post-procedure to promote comfort and cleanliness
-Patients should be educated on signs of infection or worsening pain, which may indicate an abscess.

Management And Follow Up

Monitoring And Adjustment:
-Regular follow-up appointments are scheduled, typically every 1-4 weeks depending on the type of seton and patient progress
-Draining setons are monitored for patency and drainage
-Cutting setons are gradually tightened as planned, with the patient often instructed on how to do this at home with nurse supervision
-Loose setons are checked for patency and drainage.
Advancing The Seton:
-For cutting setons, the gradual tightening is key
-The interval and amount of tightening are determined by the surgeon based on the patient's pain tolerance and the visible effect on the surrounding tissue
-The goal is slow, controlled division to allow for sphincter muscle regeneration and minimize incontinence.
Definitive Treatment And Healing:
-Healing occurs when the fistula tract closes completely, and the external opening resolves
-This can take weeks to months
-Once the tract has closed and there is no longer any discharge, the seton can be removed
-In some cases, especially with long-standing or complex fistulas, a definitive surgical procedure like fistulotomy or advancement flap may be performed after the seton has facilitated tract maturation or drainage.

Complications

Early Complications:
-Pain is common
-Bleeding may occur during or after insertion
-Abscess formation is a significant concern if drainage is inadequate or if the seton becomes occluded
-Infection of the tract or surrounding tissues can also occur.
Late Complications:
-The most feared complication is iatrogenic fecal incontinence, particularly with cutting setons if not managed appropriately
-Recurrent fistula or failure of healing can also occur
-Skin irritation or breakdown around the external opening is a possibility
-Stenosis of the anal canal may develop if healing leads to excessive fibrosis.
Prevention And Management:
-Adequate pain control and hygiene are essential
-Close monitoring for signs of infection or abscess is crucial, requiring prompt drainage if necessary
-Careful technique during seton placement and gradual, controlled tightening of cutting setons are key to minimizing incontinence
-Patient education regarding hygiene and warning signs is vital for successful management and complication avoidance.

Key Points

Exam Focus:
-Understand the different types of setons (draining, cutting, loose) and their specific indications and mechanisms of action
-Be prepared to describe the technique of insertion and postoperative management, including the concept of gradual tightening for cutting setons
-Know the indications and contraindications for seton placement in complex anal fistulas.
Clinical Pearls:
-MRI fistula protocol is invaluable for preoperative planning
-Patient selection and education are paramount for compliance
-For cutting setons, emphasize the importance of gradual tightening to preserve continence
-Consider seton placement as a tool to facilitate healing and prevent incontinence, rather than a definitive cure in itself for all cases.
Common Mistakes:
-Failure to adequately assess fistula anatomy preoperatively
-Inadequate drainage leading to abscess formation
-Aggressive or too rapid tightening of cutting setons resulting in incontinence
-Neglecting patient education leading to poor compliance or missed warning signs
-Mismanaging fistulas in patients with Crohn's disease, where conservative measures are often preferred.