Overview

Definition:
-Open right hemicolectomy is a surgical procedure involving the removal of the ascending colon and the terminal ileum, along with the associated mesentery and regional lymph nodes
-It is typically performed for benign or malignant conditions affecting the right side of the colon
-The remaining segments of the colon and ileum are then reconnected, usually via an ileocolic anastomosis.
Epidemiology:
-Right hemicolectomy is one of the most common colonic resections performed worldwide
-Indications vary by geographic region and disease prevalence, with appendicular abscess, Crohn's disease, and right-sided colon cancer being frequent causes in India
-The incidence of colon cancer is rising, contributing to the demand for hemicolectomies.
Clinical Significance:
-This procedure is crucial for managing a spectrum of diseases impacting the cecum, ascending colon, and hepatic flexure, ranging from appendicular abscesses and inflammatory bowel disease to colorectal cancer
-Proficiency in open right hemicolectomy is fundamental for surgical residents preparing for DNB and NEET SS examinations, requiring a thorough understanding of its indications, technical nuances, and potential complications to ensure optimal patient outcomes.

Indications

Malignancy:
-Colorectal cancer involving the cecum, ascending colon, or hepatic flexure
-Staging and lymph node dissection are critical components
-Lymph node yield is paramount for accurate staging and prognosis.
Benign Conditions:
-Inflammatory conditions such as Crohn's disease affecting the terminal ileum or cecum
-Complicated appendicitis with abscess or perforation that cannot be managed non-operatively
-Intestinal obstruction due to adhesions or malignancy
-Diverticular disease rarely necessitates right hemicolectomy but can be an indication if complicated.
Other Indications:
-Ischemic colitis affecting the right colon
-Trauma to the right colon
-Benign tumors like polyps that are too large or invasive for endoscopic removal
-Familial adenomatous polyposis (FAP) or hereditary non-polyposis colorectal cancer (HNPCC) with involvement of the right colon.

Preoperative Preparation

Patient Evaluation:
-Thorough history, physical examination, and assessment of comorbidities
-Evaluation of nutritional status and performance status (ECOG/KPS score).
Bowel Preparation:
-Mechanical bowel preparation with polyethylene glycol or sodium phosphate solution the day before surgery
-Oral antibiotics may be administered in select cases, particularly for elective oncologic resections.
Anesthesia Considerations:
-General anesthesia with endotracheal intubation
-Epidural anesthesia for postoperative pain management can be considered
-Fluid management and hemodynamic monitoring are essential.
Imaging And Staging:
-CT scan of the abdomen and pelvis for staging of malignancy and assessment of spread
-Colonoscopy to rule out synchronous lesions in the remaining colon
-Blood work including complete blood count, electrolytes, renal and liver function tests, coagulation profile, and tumor markers (CEA for malignancy).

Procedure Steps

Incision And Exposure:
-A midline or right paramedian incision is typically used
-The abdomen is explored to confirm resectability and rule out metastatic disease
-Mobilization of the right colon involves division of the white line of Toldt, freeing the ascending colon and hepatic flexure from the retroperitoneum.
Vascular Control And Mesenteric Division:
-Identification and ligation of the ileocolic artery and vein, and the right colic artery and vein if present
-Division of the mesentery is performed from the root to the bowel, ensuring adequate margins for lymph node dissection in oncologic cases.
Bowel Transection And Anastomosis:
-Transection of the terminal ileum approximately 5-10 cm from the ileocecal valve and transection of the transverse colon at or distal to the hepatic flexure
-The specimen is removed
-An end-to-end or side-to-side ileocolic anastomosis is fashioned using staplers or sutures
-The mesenteric defect is repaired.
Closure:
-Inspection for hemostasis and watertight anastomosis
-The abdominal wall is closed in layers
-Drains are typically not required unless there is gross contamination or concern for anastomotic leak.

Postoperative Care

Pain Management:
-Multimodal analgesia including IV opioids, NSAIDs, and epidural anesthesia if used
-Patient-controlled analgesia (PCA) can be beneficial
-Early mobilization is encouraged.
Fluid And Electrolyte Balance:
-Intravenous fluids are administered to maintain hydration and electrolyte balance
-Monitoring of urine output and serum electrolytes is crucial
-Nasogastric decompression may be used if paralytic ileus is present, though usually not routinely required.
Dietary Advancement:
-Gradual advancement of diet as tolerated, starting with clear liquids and progressing to solids
-Patients are encouraged to resume normal bowel function
-Monitoring for return of bowel sounds and flatus.
Monitoring For Complications:
-Close monitoring for signs of infection, anastomotic leak (fever, tachycardia, abdominal pain, peritonitis), ileus, bleeding, and deep vein thrombosis (DVT)
-Prophylactic antibiotics are continued for a short duration
-DVT prophylaxis with subcutaneous heparin and compression stockings is standard.

Complications

Early Complications:
-Anastomotic leak: the most feared complication, leading to peritonitis and sepsis
-Wound infection and dehiscence
-Intra-abdominal abscess formation
-Postoperative ileus
-Hemorrhage from surgical site or staple line
-Injury to adjacent organs (e.g., ureter, duodenum).
Late Complications:
-Bowel obstruction due to adhesions
-Incisional hernia at the site of abdominal closure
-Stricture formation at the anastomosis
-Chronic pain
-Altered bowel habits
-Recurrence of disease if malignancy was the indication.
Prevention Strategies:
-Meticulous surgical technique with adequate blood supply to the bowel ends
-Careful handling of tissues to minimize trauma
-Secure and watertight anastomosis
-Optimal bowel preparation and perioperative antibiotics
-Prompt recognition and management of any signs of complications
-DVT prophylaxis and early mobilization.

Key Points

Exam Focus:
-Indications for right hemicolectomy, including oncologic vs
-benign
-Key steps in mobilization and vascular control
-Principles of ileocolic anastomosis (stapled vs
-hand-sewn)
-Common causes and signs of anastomotic leak
-Lymph node yield in oncologic resections is critical for staging.
Clinical Pearls:
-Always confirm resectability with a thorough abdominal exploration
-Ensure adequate vascular supply to both ends before anastomosis
-Meticulous repair of the mesenteric defect prevents internal hernias
-Consider the use of indocyanine green (ICG) fluorescence angiography to assess bowel perfusion before anastomosis
-Early ambulation is key for reducing postoperative complications.
Common Mistakes:
-Inadequate lymphadenectomy in oncologic cases
-Insufficient bowel margins
-Compromised blood supply to the anastomotic ends
-Failure to repair the mesenteric defect
-Delay in recognizing and managing anastomotic leak
-Inadequate bowel preparation leading to increased infection risk.