Overview

Definition:
-Decortication for empyema is a surgical procedure to remove the thickened fibrous peel (necrotic debris and inflammatory exudate) from the visceral and parietal pleura, typically performed via Video-Assisted Thoracoscopic Surgery (VATS)
-This is crucial for re-expansion of the lung and resolution of chronic empyema.
Epidemiology:
-Empyema incidence varies globally, often associated with pneumonia, thoracic surgery, or trauma
-The incidence of chronic empyema requiring decortication is lower but still significant, especially in developing countries
-Risk factors include delayed treatment of pneumonia, immunocompromise, and poor nutritional status.
Clinical Significance:
-Untreated or inadequately treated empyema can lead to significant morbidity and mortality
-Decortication is vital for lung re-expansion, preventing lung entrapment, and resolving chronic infection, thereby improving respiratory function and quality of life for patients
-It is a key procedure in thoracic surgical training for DNB and NEET SS examinations.

Indications

Indications For Surgery:
-Failure of medical management or simple drainage
-loculated empyema
-chronic empyema with thick peel
-persistent fever and sepsis despite antibiotics
-lung entrapment by peel
-significant hemoptysis associated with empyema.
Timing Of Surgery:
-Early decortication (within the first few weeks of empyema onset) generally leads to better outcomes
-However, VATS decortication can be performed even in chronic cases with appropriate patient selection and preparation.
Contraindications:
-Severe underlying lung disease precluding adequate ventilation post-re-expansion
-significant coagulopathy
-active sepsis that cannot be controlled medically
-widespread pleural tumor involvement
-patient refusal or inability to tolerate anesthesia.

Diagnostic Approach

History Taking:
-Detailed history of preceding pneumonia, duration of symptoms, fevers, chills, cough, dyspnea, chest pain
-previous thoracic interventions
-comorbidities
-recent travel or exposures.
Physical Examination:
-Assess vital signs (fever, tachypnea, tachycardia)
-Examine chest for asymmetry, decreased breath sounds, dullness to percussion, egophony
-Palpate for chest wall tenderness or subcutaneous emphysema.
Imaging Modalities:
-Chest X-ray (PA and lateral) to show effusion, loculations, and pleural thickening
-Ultrasound of the chest to guide aspiration and identify loculations
-CT scan of the thorax is essential for delineating the extent of empyema, assessing the thickness and location of the peel, and evaluating underlying lung parenchyma
-MRI may be used if malignancy is suspected.
Laboratory Investigations:
-Complete Blood Count (CBC) for leukocytosis and anemia
-Erythrocyte Sedimentation Rate (ESR) and C-reactive protein (CRP) for inflammatory markers
-Blood cultures to identify causative organism
-Sputum Gram stain and culture
-Pleural fluid analysis (cytology, microbiology, pH, glucose, LDH).

Surgical Management Vats Decortication

Preoperative Preparation:
-Optimization of patient's nutritional status and cardiorespiratory reserve
-Administration of appropriate antibiotics
-Chest physiotherapy
-Preoperative antibiotics covering common pathogens (e.g., cephalosporins, clindamycin).
Vats Procedure Steps:
-General anesthesia with double-lumen endotracheal tube for single-lung ventilation
-Insertion of 2-3 ports in the chest wall (camera port, instrument ports)
-Insufflation of CO2 at low pressure may be used to improve visualization
-Identification of the peel
-Careful dissection of the peel from the visceral and parietal pleura using electrocautery, ultrasonic dissector, or harmonic scalpel
-Lung mobilization and release
-Lavage of the pleural space
-Placement of one or two chest tubes for drainage and lung re-expansion
-The goal is complete removal of the peel and complete lung expansion.
Instrumentation: Thoracoscope, light source, video monitor, insufflator (optional), graspers, dissectors (e.g., ultrasonic dissector, harmonic scalpel), scissors, suction, chest tube insertion device.
Anesthesia Considerations: Requires general anesthesia with ability for lung isolation (double-lumen tube or bronchial blocker) for optimal surgical field and lung deflation.

Postoperative Care

Chest Tube Management:
-Chest tubes are typically connected to an underwater seal drainage system, with or without suction
-Monitor for drainage amount, color, and air leak
-Chest X-ray to assess lung expansion and tube position
-Early mobilization is encouraged.
Pain Management:
-Effective multimodal analgesia including patient-controlled analgesia (PCA), epidural analgesia, or intercostal nerve blocks
-Oral analgesics as needed.
Antibiotic Therapy: Continue intravenous antibiotics tailored to pleural fluid culture results for an appropriate duration (often 7-14 days or longer depending on clinical response).
Respiratory Support:
-Encourage deep breathing exercises, incentive spirometry, and early ambulation to prevent atelectasis and pneumonia
-Supplemental oxygen as needed
-Weaning from mechanical ventilation if required.

Complications

Early Complications:
-Persistent air leak
-bleeding
-intrathoracic infection
-bronchopleural fistula
-phrenic nerve injury
-residual hemothorax or loculations
-failure of lung re-expansion
-cardiovascular instability.
Late Complications:
-Chronic pain
-pleural thickening
-lung entrapment if decortication was incomplete
-respiratory insufficiency
-fungal empyema
-empyema necessitans.
Prevention Strategies:
-Meticulous surgical technique to minimize trauma
-thorough lavage to remove debris
-adequate chest tube drainage
-prompt management of air leaks
-early and effective pain control
-aggressive chest physiotherapy and mobilization
-judicious antibiotic use.

Prognosis

Factors Affecting Prognosis:
-Stage of empyema at presentation (e.g., FEV stages)
-causative organism
-patient's immune status and comorbidities
-completeness of decortication
-promptness of surgical intervention
-post-operative complications.
Outcomes:
-Successful VATS decortication leads to significant improvement in symptoms, lung function, and quality of life
-Complete resolution of infection is expected in most cases
-Mortality rates are significantly lower for early intervention and VATS compared to open thoracotomy for empyema.
Follow Up:
-Regular follow-up appointments with chest X-rays to monitor lung expansion and pleural space
-Assessment of respiratory function
-Rehabilitation may be necessary
-Duration of follow-up depends on complexity and resolution.

Key Points

Exam Focus:
-Key indications for VATS decortication versus simple drainage
-steps of VATS decortication
-common complications and their management
-factors influencing prognosis in empyema
-interpretation of CT findings in empyema.
Clinical Pearls:
-Thickened peel in chronic empyema is often avascular and can be dissected from the lung parenchyma
-Always ensure complete release of the peel for full lung re-expansion
-Consider an intraoperative bronchoscopy if a bronchopleural fistula is suspected
-Chest tube removal criteria: minimal drainage (<100-150 ml/24h), no air leak, and adequate lung expansion on X-ray.
Common Mistakes:
-Delaying surgical intervention in the presence of sepsis or lung entrapment
-Incomplete peel removal leading to persistent symptoms
-Inadequate pain management contributing to poor respiratory effort
-Overlooking underlying lung parenchymal disease during CT interpretation.