Overview

Definition:
-Peripheral intravenous (IV) access is crucial for fluid, medication, and blood product administration
-Difficult vascular access (DVA) in pediatric patients, especially neonates and infants, poses significant challenges due to smaller vessel size, obesity, dehydration, or repeated cannulation attempts
-Ultrasound guidance (USG) has emerged as a valuable tool to improve first-attempt success rates and reduce complications associated with PIV insertion in these challenging scenarios.
Epidemiology:
-The incidence of difficult vascular access in pediatric patients varies widely, with some studies reporting up to 50% of neonates and infants requiring multiple attempts for peripheral venous cannulation
-Factors contributing to DVA include prematurity, prematurity-related complications, dehydration, obesity, darker skin pigmentation, and chronic medical conditions requiring frequent IV access.
Clinical Significance:
-Successful and timely peripheral IV access is vital for effective management of critically ill pediatric patients, including resuscitation, antibiotic administration, analgesia, and nutritional support
-Failed attempts can lead to increased patient distress, prolonged procedural time, multiple venipunctures, increased risk of complications like hematoma, nerve injury, and infection, and delayed treatment
-Ultrasound guidance significantly enhances the ability of clinicians to achieve successful PIV access in these challenging cases, thereby improving patient outcomes and reducing healthcare costs.

Age Considerations

Neonate:
-Smaller vein diameter, fragile vessels, limited tissue depth, increased risk of extravasation
-Use of high-frequency linear transducers is essential
-Careful attention to sterile technique is paramount.
Infant:
-Larger vessel size compared to neonates but still challenging due to movement and limited peripheral veins
-May use slightly lower frequency transducers if tissue depth is greater
-Arm and leg veins are common sites.
Child:
-Veins are generally more easily visualized, but obesity or dehydration can still pose challenges
-Dynamic real-time imaging is still beneficial for confirming vessel patency and guiding the needle.
Factors Influencing Access: Dehydration, obesity, previous IV lines, edema, dark skin pigmentation, and patient anxiety/movement.

Diagnostic Approach

History Taking:
-Inquire about previous IV access difficulties, duration of illness, fluid intake and output, presence of vomiting or diarrhea, and current medications
-Assess for signs of dehydration or edema
-Ascertain previous successful or unsuccessful IV sites.
Physical Examination:
-Assess skin turgor, mucous membrane moisture, and capillary refill time to evaluate hydration status
-Examine peripheral veins visually and by palpation, noting any distension, tortuosity, or absence
-Evaluate for edema or hematoma from previous attempts
-Assess body mass index for potential obesity challenges.
Ultrasound Technique:
-Use a high-frequency linear transducer (e.g., 10-15 MHz)
-Apply sterile gel and cover the probe with a sterile sheath and glove
-Orient the probe in a longitudinal plane over the suspected vessel
-Identify veins based on anechoic, compressible, pulsatile (artery) or non-pulsatile (vein) tubular structures
-Evaluate for thrombus, anatomical variation, and surrounding structures
-Dynamic assessment: compress the vessel to confirm compressibility and patency.
Imaging Modalities:
-High-resolution ultrasound imaging is the primary modality for real-time visualization of peripheral veins
-Avoidance of Doppler unless specifically assessing flow in complex cases, as it can obscure direct visualization of the needle tip.

Management

Initial Preparation:
-Ensure adequate lighting, necessary equipment (IV catheters of appropriate size, syringes, sterile gel, sterile probe cover, sterile gloves, antiseptic solution, dressing), and a calm environment
-Sedation or topical anesthetic may be considered for older children or anxious patients.
Ultrasound Guided Insertion Technique:
-Place the probe in a longitudinal plane over the target vein
-Identify the vein and surrounding structures
-Insert the IV catheter at a 30-45 degree angle, visualizing the needle tip in real-time under ultrasound guidance
-Advance the needle slowly, maintaining visualization
-Once the needle enters the lumen, flashback of blood should be observed
-Advance the catheter while withdrawing the needle
-Secure the IV line with appropriate dressing.
Catheter Selection:
-Select the smallest gauge catheter that can deliver the required therapy, typically 24-28 gauge for neonates and infants, and 20-24 gauge for older children
-Use appropriate length catheters to minimize manipulation.
Site Selection:
-Common sites include antecubital fossa, forearm, hand dorsum, saphenous vein (medial malleolus area), and foot dorsum
-Ultrasound can identify veins not apparent on physical examination.
Alternatives If Failed: If peripheral access remains elusive after multiple ultrasound-guided attempts, consider central venous access (if indicated and expertise is available) or intraosseous access as an alternative.

Complications

Early Complications:
-Hematoma formation
-Pain
-Nerve injury
-Artery puncture
-Incomplete insertion or dislodgement
-Extravasation of infusate
-Phlebitis.
Late Complications:
-Infection (local or systemic)
-Occlusion of the vein
-Thrombosis
-Catheter-related bloodstream infection (CRBSI).
Prevention Strategies:
-Utilize ultrasound guidance to minimize venipuncture attempts
-Employ proper sterile technique
-Select appropriate catheter size
-Secure the IV line adequately
-Monitor the IV site regularly for signs of complications
-Educate nursing staff on early detection and management of complications.

Prognosis

Factors Affecting Prognosis:
-The prognosis for successful peripheral IV access using ultrasound guidance in difficult cases is generally excellent
-Factors influencing success include operator experience, ultrasound equipment quality, patient factors (e.g., degree of dehydration, obesity), and timely utilization of the technique.
Outcomes With Ultrasound Guidance:
-Studies consistently demonstrate higher first-attempt success rates, fewer venipunctures, reduced procedure time, and decreased patient and caregiver distress when ultrasound guidance is used for PIV insertion in difficult access pediatric patients
-This translates to more efficient care and improved patient experience.
Follow Up:
-Routine monitoring of the IV site for signs of infiltration, infection, or phlebitis is essential throughout the duration of therapy
-Prompt removal of the IV catheter once therapy is complete or if complications arise.

Key Points

Exam Focus:
-Understand the indications for ultrasound guidance in pediatric IV access
-Be familiar with the specific ultrasound probe types and settings for neonates and infants
-Recognize potential complications and their management
-Differentiate between arterial and venous visualization on ultrasound.
Clinical Pearls:
-Always use sterile technique with ultrasound probe covers
-Start with a longitudinal view of the vessel
-Compress the vein gently to confirm its nature and patency
-Advance the needle tip slowly and steadily
-Look for flashback of blood *after* the needle enters the lumen
-Consider topical anesthetics or mild sedation for very distressed children.
Common Mistakes:
-Using inappropriate transducer frequency or probe cover
-Inadequate visualization of the needle tip
-Attempting insertion without proper sterile technique
-Misinterpreting arterial pulsations as venous flashback
-Failing to stop advancing the catheter once flashback is achieved.